Pathway	L-c-vs-L-ins (1184)	All (6799)	Pvalue	Qvalue	Pathway ID	Genes	KOs
Cytokine-cytokine receptor interaction	92	259	7.53E-13	1.20E-10	ko04060	XLOC_003373;XLOC_014419;XLOC_020245;XLOC_022319;XLOC_023072;gene2866;gene2865;gene3089;gene3108;gene3310;gene3315;gene3526;gene3646;gene4122;gene4363;gene4444;gene4445;gene4558;gene4648;gene4926;gene4980;gene5123;gene5200;gene5289;gene5545;gene5731;gene6000;gene6203;gene7041;gene7043;gene7154;gene7454;gene7631;gene8147;gene8489;gene8682;gene8862;gene8961;gene937;gene9529;gene9935;gene9984;gene9998;gene10158;gene10468;gene10722;gene11386;gene11499;gene11788;gene11995;gene12936;gene12945;gene1325;gene13905;gene15463;gene15879;gene15905;gene16024;gene16213;gene16288;gene16576;gene1649;gene16619;gene16666;gene16667;gene16921;gene17289;gene17606;gene18259;gene18587;gene18693;gene1852;gene18977;gene19024;gene19256;gene20211;gene20451;gene20619;gene20646;gene20847;gene21751;gene21752;gene21754;gene21876;gene21896;gene22155;gene22597;gene23065;gene23236;gene23273;gene2492;gene263	K06854+K05416+K05433+K05067+K16062+K04193+K04193+K03161+K05134+K04387+K04723+K04193+K05477+K05089+K05141+K05090+K05089+K05061+K16597+K04667+K04721+K05143+K13578+K04182+K05080+K04662+K05155+K13377+K04188+K04188+K04662+K05505+K04738+K04519+K05162+K05076+K05425+K12671+K13578+K05092+K05477+K05069+K17386+K05448+K04190+K04670+K05165+K05090+K16597+K05474+K05450+K10033+K05150+K14625+K04667+K05099+K04674+K05423+K03160+K04184+K05135+K04675+K03160+K12964+K16597+K05448+K05074+K12964+K13375+K05417+K04176+K10032+K05050+K14625+K05143+K05072+K04519+K04722+K04662+K05058+K05506+K05505+K05506+K04388+K05408+K13567+K05070+K05152+K04722+K12671+K04179+K05482
"Glycine, serine and threonine metabolism"	29	57	7.10E-09	5.64E-07	ko00260	XLOC_020404;XLOC_020405;gene3206;gene4752;gene4930;gene5134;gene6063;gene6064;gene7198;gene7729;gene843;gene8956;gene10434;gene10929;gene11385;gene11600;gene12228;gene12388;gene1239;gene12746;gene13685;gene14377;gene14378;gene14952;gene15221;gene16714;gene17304;gene20114;gene21065	K00544+K00544+K02437+K00613+K00600+K00643+K00544+K00544+K15789+K00831+K00314+K00049+K01754+K00600+K00108+K00276+K01834+K00605+K00827+K00542+K00273+K00544+K00544+K00306+K00058+K17989+K00049+K00315+K00273
Carbon metabolism	48	149	6.52E-06	3.45E-04	ko01200	gene2943;gene3013;gene4057;gene4254;gene4442;gene4488;gene4777;gene4930;gene5394;gene6229;gene6325;gene7128;gene7294;gene7697;gene7729;gene9292;gene10434;gene10929;gene10996;gene11322;gene11382;gene12228;gene12388;gene12592;gene1294;gene13316;gene13866;gene14074;gene14355;gene1439;gene14754;gene15221;gene15834;gene15959;gene16714;gene16742;gene16837;gene16943;gene18014;gene18098;gene18122;gene18899;gene18936;gene20361;gene21402;gene2085;gene22070;gene23187	K00031+K00121+K07514+K05606+K00033+K00235+K00140+K00600+K13937+K00140+K11517+K03781+K00626+K12407+K00831+K00850+K01754+K00600+K03841+K01623+K00615+K01834+K00605+K00029+K00850+K00134+K00121+K01948+K01623+K00164+K01895+K00058+K00164+K00025+K17989+K03841+K00844+K01623+K01053+K01783+K00164+K00029+K01803+K00164+K01689+K01958+K11517+K01623
Metabolism of xenobiotics by cytochrome P450	19	42	2.54E-05	1.01E-03	ko00980	XLOC_002669;XLOC_009722;XLOC_013621;gene3013;gene347;gene4042;gene4330;gene5340;gene5625;gene9609;gene10132;gene10841;gene1120;gene13866;gene13987;gene1838;gene22539;gene2259;gene23446	K00699+K00699+K00699+K00121+K01253+K00699+K00799+K00799+K07408+K00078+K00079+K00699+K00799+K00121+K00129+K00799+K00699+K00799+K00799
Drug metabolism - cytochrome P450	19	44	5.62E-05	1.79E-03	ko00982	XLOC_002669;XLOC_009722;XLOC_013621;gene3013;gene4042;gene4330;gene5340;gene10524;gene10525;gene10841;gene1120;gene13866;gene13987;gene1838;gene19599;gene19601;gene22539;gene2259;gene23446	K00699+K00699+K00699+K00121+K00699+K00799+K00799+K00485+K00485+K00699+K00799+K00121+K00129+K00799+K00485+K00485+K00699+K00799+K00799
Intestinal immune network for IgA production	20	50	0.000132209	3.25E-03	ko04672	XLOC_020245;XLOC_024422;gene3089;gene7768;gene9277;gene12629;gene1325;gene1475;gene16213;gene16288;gene16309;gene16619;gene16988;gene17289;gene17723;gene18259;gene19059;gene19241;gene21015;gene23041	K05433+K06752+K03161+K06752+K13073+K06710+K05150+K13073+K03160+K04184+K10785+K03160+K06483+K05074+K06752+K13375+K06752+K10785+K05412+K06752
Pentose phosphate pathway	16	36	0.000143179	3.25E-03	ko00030	gene4442;gene5394;gene9292;gene10996;gene11322;gene11382;gene11838;gene12058;gene1294;gene14355;gene16742;gene16943;gene18014;gene18098;gene21076;gene23187	K00033+K13937+K00850+K03841+K01623+K00615+K01835+K15779+K00850+K01623+K03841+K01623+K01053+K01783+K15779+K01623
One carbon pool by folate	12	24	0.000253413	5.04E-03	ko00670	gene4930;gene5240;gene8396;gene9393;gene10929;gene11726;gene12388;gene13196;gene17245;gene19167;gene19495;gene20180	K00600+K13403+K00289+K00288+K00600+K00289+K00605+K13402+K00288+K00287+K13990+K00289
Arachidonic acid metabolism	24	68	0.000290983	5.14E-03	ko00590	XLOC_015149;XLOC_019383;XLOC_019392;XLOC_024611;gene3522;gene5425;gene6642;gene7722;gene9990;gene10132;gene10502;gene11412;gene11411;gene12087;gene12717;gene14170;gene14169;gene14709;gene15001;gene15344;gene15345;gene19057;gene21714;gene23534	K07418+K16342+K16342+K16342+K07418+K01831+K11987+K00432+K16343+K00079+K07418+K08022+K08022+K01047+K00432+K16342+K16342+K00432+K07418+K18592+K18592+K15729+K01047+K16342
Steroid biosynthesis	12	25	0.000410728	6.53E-03	ko00100	gene413;gene5666;gene10824;gene13627;gene16121;gene1600;gene17875;gene19271;gene20157;gene20375;gene21306;gene23734	K07419+K01852+K00222+K00637+K07438+K01824+K07750+K07436+K12298+K01052+K12298+K12298
Porphyrin and chlorophyll metabolism	16	40	0.000614129	8.80E-03	ko00860	XLOC_002669;XLOC_009722;XLOC_013621;XLOC_023873;gene4042;gene471;gene5134;gene5175;gene10841;gene11146;gene12191;gene1378;gene14390;gene19852;gene19978;gene22539	K00699+K00699+K00699+K00214+K00699+K14163+K00643+K00228+K00699+K00510+K05901+K02259+K00214+K13624+K00231+K00699
Linoleic acid metabolism	14	33	0.000663927	8.80E-03	ko00591	XLOC_015149;XLOC_019383;XLOC_019392;XLOC_024611;gene3522;gene9990;gene10102;gene10502;gene12087;gene14170;gene14169;gene15001;gene21714;gene23534	K07418+K16342+K16342+K16342+K07418+K16343+K07424+K07418+K01047+K16342+K16342+K07418+K01047+K16342
Pentose and glucuronate interconversions	15	39	0.001454765	1.78E-02	ko00040	XLOC_002669;XLOC_009722;XLOC_013621;gene3584;gene4042;gene428;gene9609;gene10760;gene10841;gene13808;gene14879;gene16249;gene18098;gene18726;gene22539	K00699+K00699+K00699+K00963+K00699+K00008+K00078+K01805+K00699+K03331+K00128+K00011+K01783+K00854+K00699
PPAR signaling pathway	27	89	0.001841842	1.90E-02	ko03320	gene3532;gene3641;gene4032;gene4031;gene4057;gene4754;gene5877;gene5918;gene6636;gene6674;gene7165;gene7841;gene8473;gene8649;gene11918;gene132;gene12749;gene14450;gene1453;gene17024;gene17213;gene1717;gene17722;gene21786;gene22603;gene2550;gene2654	K08526+K08745+K15013+K15013+K07514+K08746+K07294+K01897+K15013+K06086+K01897+K00864+K06272+K08751+K01596+K00507+K08767+K01897+K00507+K00232+K01897+K07294+K01596+K00489+K08761+K08765+K08746
Glycolysis / Gluconeogenesis	27	89	0.001841842	1.90E-02	ko00010	gene3013;gene5369;gene6556;gene7697;gene9292;gene10996;gene11322;gene11838;gene11918;gene12029;gene12058;gene12228;gene1294;gene13316;gene13866;gene13987;gene14355;gene14754;gene14879;gene16742;gene16837;gene16943;gene17722;gene18936;gene21076;gene21402;gene23187	K00121+K00016+K00149+K12407+K00850+K03841+K01623+K01835+K01596+K00016+K15779+K01834+K00850+K00134+K00121+K00129+K01623+K01895+K00128+K03841+K00844+K01623+K01596+K01803+K15779+K01689+K01623
Biosynthesis of amino acids	29	98	0.001944177	1.90E-02	ko01230	gene2943;gene3395;gene4930;gene7729;gene793;gene9292;gene979;gene10434;gene10929;gene11322;gene11382;gene12228;gene1294;gene13316;gene14074;gene14355;gene14496;gene15089;gene15221;gene16714;gene16943;gene175;gene18098;gene18936;gene20804;gene21402;gene2085;gene23187;gene23687	K00031+K00286+K00600+K00831+K00789+K00850+K01940+K01754+K00600+K01623+K00615+K01834+K00850+K00134+K01948+K01623+K00286+K00611+K00058+K17989+K01623+K12657+K01783+K01803+K11067+K01689+K01958+K01623+K01476
Fructose and mannose metabolism	16	44	0.002036523	1.90E-02	ko00051	gene428;gene9292;gene10760;gene10996;gene11322;gene1294;gene14355;gene16162;gene16249;gene16742;gene16837;gene16943;gene18936;gene2197;gene23187;gene253	K00008+K00850+K01805+K03841+K01623+K00850+K01623+K17497+K00011+K03841+K00844+K01623+K01803+K19030+K01623+K00966
Insulin signaling pathway	50	195	0.002177237	1.92E-02	ko04910	gene3264;gene3363;gene3518;gene5035;gene5064;gene5153;gene5367;gene6163;gene6629;gene6674;gene7697;gene7925;gene8133;gene8165;gene8588;gene9318;gene9502;gene9634;gene10242;gene10996;gene1141;gene11753;gene11760;gene11918;gene1180;gene12415;gene12501;gene12794;gene12921;gene13658;gene14141;gene14217;gene14291;gene1413;gene15128;gene1486;gene16004;gene16327;gene16742;gene16837;gene17669;gene17722;gene17898;gene18990;gene1969;gene21302;gene21982;gene22154;gene22454;gene22581	K06279+K07200+K04372+K04438+K15909+K04527+K02833+K07202+K04372+K06086+K12407+K00871+K07192+K15909+K16172+K07193+K07198+K04696+K04739+K03841+K00922+K07188+K04707+K01596+K07189+K07188+K07195+K07187+K04440+K02183+K07187+K04694+K04688+K03259+K02649+K06269+K04526+K07192+K03841+K00844+K02649+K01596+K04696+K02649+K00871+K07189+K00688+K07200+K07189+K07187
Adipocytokine signaling pathway	30	107	0.004039901	3.38E-02	ko04920	gene3363;gene3532;gene4032;gene4031;gene4363;gene4502;gene5877;gene5918;gene6163;gene6636;gene7165;gene8588;gene9502;gene9634;gene11918;gene1206;gene12433;gene12794;gene12921;gene14141;gene14450;gene15896;gene17148;gene17213;gene1717;gene17722;gene17898;gene22154;gene22581;gene2550	K07200+K08526+K15013+K15013+K05141+K07293+K07294+K01897+K07202+K15013+K01897+K16172+K07198+K04696+K01596+K04447+K07299+K07187+K04440+K07187+K01897+K07359+K18052+K01897+K07294+K01596+K04696+K07200+K07187+K08765
Arginine and proline metabolism	20	64	0.004741162	3.75E-02	ko00330	gene2914;gene3395;gene4752;gene6556;gene7149;gene106;gene11327;gene11985;gene12746;gene12963;gene13685;gene14284;gene14496;gene14879;gene16513;gene175;gene18067;gene18400;gene21065;gene23687	K00472+K00286+K00613+K00149+K00933+K00819+K11394+K11182+K00542+K01480+K00273+K18123+K00286+K00128+K00933+K12657+K00657+K00933+K00273+K01476
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	11	28	0.005094032	3.75E-02	ko00532	gene5044;gene6798;gene8399;gene107;gene10947;gene126;gene1336;gene13873;gene13990;gene14207;gene16508	K00746+K03193+K01017+K08106+K00746+K01020+K08106+K03419+K13499+K04742+K01794
Fatty acid degradation	18	56	0.005185285	3.75E-02	ko00071	gene3013;gene4032;gene4031;gene4057;gene5918;gene6556;gene6636;gene7165;gene7294;gene10202;gene114;gene11288;gene13866;gene14450;gene14879;gene17024;gene17213;gene2550	K00121+K15013+K15013+K07514+K01897+K00149+K15013+K01897+K00626+K07509+K09478+K13238+K00121+K01897+K00128+K00232+K01897+K08765
Glyoxylate and dicarboxylate metabolism	13	36	0.005607957	3.88E-02	ko00630	gene3206;gene4254;gene4930;gene6325;gene7128;gene7294;gene8956;gene10929;gene12388;gene14284;gene15959;gene17304;gene22070	K02437+K05606+K00600+K11517+K03781+K00626+K00049+K00600+K00605+K18123+K00025+K00049+K11517
Glycerolipid metabolism	24	83	0.006318797	4.06E-02	ko00561	gene3556;gene4166;gene463;gene4867;gene6556;gene6572;gene7700;gene7841;gene8922;gene9855;gene10658;gene13167;gene14879;gene15912;gene16249;gene16824;gene17800;gene20157;gene21096;gene21306;gene21385;gene22860;gene2257;gene23734	K01080+K01080+K11155+K00901+K00149+K15728+K13506+K00864+K01046+K15728+K15728+K16816+K00128+K11160+K00011+K01080+K01080+K12298+K11160+K12298+K00901+K14073+K19007+K12298
Phagosome	50	205	0.00638628	4.06E-02	ko04145	XLOC_006672;XLOC_024422;gene509;gene647;gene6597;gene6925;gene7331;gene7741;gene7768;gene8581;gene8720;gene9019;gene9063;gene9324;gene9834;gene9947;gene9948;gene10669;gene10670;gene1062;gene1065;gene12972;gene1301;gene13347;gene13621;gene14722;gene14915;gene16623;gene16625;gene16622;gene16624;gene16744;gene17263;gene17421;gene17415;gene17723;gene18696;gene18800;gene19059;gene21048;gene21169;gene21456;gene21864;gene21987;gene22187;gene22198;gene22825;gene23041;gene23201;gene2300	K06563+K06752+K06528+K08011+K07374+K10066+K07342+K09481+K06752+K01368+K05719+K06751+K06751+K06498+K08010+K03990+K03990+K06560+K06560+K06493+K06560+K05653+K08010+K07375+K08057+K10956+K13882+K01330+K01330+K01330+K01330+K01365+K06484+K05654+K06751+K06752+K16857+K08054+K06752+K08008+K02152+K06751+K13813+K06464+K02151+K10159+K13884+K06752+K05692+K04659
Glycerophospholipid metabolism	34	129	0.006674324	4.08E-02	ko00564	XLOC_019383;XLOC_019392;XLOC_024611;gene3556;gene4166;gene4629;gene4867;gene584;gene6572;gene7700;gene8241;gene9182;gene9379;gene9855;gene9990;gene10658;gene12087;gene12200;gene13400;gene13996;gene14170;gene14169;gene14885;gene16608;gene16824;gene17800;gene2061;gene21385;gene21714;gene2257;gene23534;gene2435;gene2504;gene2551	K16342+K16342+K16342+K01080+K01080+K00006+K00901+K00968+K15728+K13506+K00649+K00968+K16860+K15728+K16343+K15728+K01047+K00894+K00111+K13516+K16342+K16342+K00999+K13515+K01080+K01080+K14286+K00901+K01047+K19007+K16342+K08729+K13510+K14156
Insulin resistance	42	168	0.007596894	4.47E-02	ko04931	gene2770;gene3052;gene3363;gene3641;gene4502;gene4754;gene4987;gene5153;gene5877;gene6163;gene6303;gene8588;gene9502;gene9634;gene1141;gene11918;gene1180;gene12433;gene12794;gene12921;gene14141;gene14218;gene14291;gene14863;gene15128;gene1486;gene16004;gene17148;gene17492;gene1717;gene17669;gene17722;gene17898;gene18990;gene21302;gene21982;gene22154;gene22454;gene22581;gene2482;gene2550;gene2654	K19662+K19518+K07200+K08745+K07293+K08746+K07593+K04527+K07294+K07202+K17902+K16172+K07198+K04696+K00922+K01596+K07189+K07299+K07187+K04440+K07187+K19662+K04688+K00820+K02649+K06269+K04526+K18052+K06068+K07294+K02649+K01596+K04696+K02649+K07189+K00688+K07200+K07189+K07187+K04373+K08765+K08746
Ascorbate and aldarate metabolism	10	27	0.01193762	6.78E-02	ko00053	XLOC_002669;XLOC_009722;XLOC_013621;gene3193;gene4042;gene6556;gene10841;gene14879;gene18014;gene22539	K00699+K00699+K00699+K00469+K00699+K00149+K00699+K00128+K01053+K00699
Peroxisome	28	107	0.01437459	7.88E-02	ko04146	gene2943;gene4057;gene4662;gene4754;gene5918;gene6325;gene6733;gene7128;gene7165;gene7795;gene8241;gene9032;gene9876;gene10743;gene13685;gene14450;gene14952;gene15110;gene15687;gene16307;gene17024;gene17213;gene19485;gene20846;gene21065;gene21070;gene22070;gene2654	K00031+K07514+K13237+K08746+K01897+K11517+K13279+K03781+K01897+K00624+K00649+K00803+K13340+K00624+K00273+K01897+K00306+K13348+K05676+K13345+K00232+K01897+K13342+K00624+K00273+K13347+K11517+K08746
Starch and sucrose metabolism	16	53	0.01544937	8.19E-02	ko00500	XLOC_002669;XLOC_009722;XLOC_013621;gene3584;gene4042;gene7697;gene10470;gene10841;gene11838;gene12058;gene15424;gene16837;gene1939;gene21076;gene21982;gene22539	K00699+K00699+K00699+K00963+K00699+K12407+K01194+K00699+K01835+K15779+K01176+K00844+K12047+K15779+K00688+K00699
Fatty acid metabolism	19	67	0.01749277	8.70E-02	ko01212	gene4032;gene4031;gene4057;gene5918;gene6636;gene7069;gene7165;gene7294;gene10202;gene114;gene132;gene14450;gene1453;gene17024;gene17213;gene18961;gene21142;gene2262;gene2550	K15013+K15013+K07514+K01897+K15013+K10703+K01897+K00626+K07509+K09478+K00507+K01897+K00507+K00232+K01897+K01074+K10203+K10244+K08765
Protein processing in endoplasmic reticulum	51	221	0.01750413	8.70E-02	ko04141	gene2985;gene3364;gene5404;gene6085;gene6366;gene7331;gene7424;gene7425;gene7626;gene7741;gene8044;gene8740;gene9166;gene9288;gene986;gene10690;gene11209;gene11222;gene1108;gene11429;gene11577;gene11734;gene11798;gene12004;gene12440;gene12921;gene13257;gene13621;gene13888;gene14387;gene14722;gene1459;gene15362;gene16373;gene16451;gene16638;gene1673;gene17061;gene18800;gene18806;gene19035;gene20070;gene2074;gene21885;gene21910;gene22125;gene22374;gene23019;gene23026;gene23246;gene2696	K09502+K02161+K10084+K13525+K09580+K07342+K11718+K09523+K04374+K09481+K09561+K13251+K10666+K04079+K09490+K12275+K13999+K09584+K03283+K01228+K12670+K10976+K14026+K09523+K11519+K04440+K03283+K08057+K10950+K09517+K10956+K07953+K08860+K10601+K03283+K07151+K04571+K12666+K08054+K14001+K09486+K14015+K14018+K14005+K10085+K14027+K03283+K06689+K08056+K02161+K09487
Toll-like receptor signaling pathway	30	120	0.02175614	1.01E-01	ko04620	XLOC_014419;gene290;gene4497;gene7171;gene7172;gene8147;gene8582;gene8862;gene8961;gene9027;gene9118;gene10648;gene1141;gene12921;gene13029;gene15128;gene16213;gene16619;gene16666;gene17606;gene17669;gene17840;gene18990;gene20451;gene21015;gene21896;gene22198;gene23036;gene23273;gene2568	K05416+K05401+K04441+K04379+K04379+K04519+K01371+K05425+K12671+K04398+K04441+K10168+K00922+K04440+K10170+K02649+K03160+K03160+K12964+K12964+K02649+K02373+K02649+K04519+K05412+K05408+K10159+K10168+K12671+K05403
VEGF signaling pathway	26	101	0.02194254	1.01E-01	ko04370	XLOC_019383;XLOC_019392;XLOC_024611;gene2770;gene3540;gene4497;gene5367;gene6642;gene8513;gene9118;gene9972;gene10158;gene1141;gene12105;gene12284;gene12730;gene13098;gene14170;gene14169;gene14218;gene15128;gene16921;gene17669;gene18990;gene19270;gene23534	K16342+K16342+K16342+K19662+K05760+K04441+K02833+K11987+K05704+K04441+K07860+K05448+K00922+K01116+K04443+K05704+K04455+K16342+K16342+K19662+K02649+K05448+K02649+K02649+K17332+K16342
Cysteine and methionine metabolism	18	64	0.02215966	1.01E-01	ko00270	XLOC_020404;XLOC_020405;gene5369;gene6063;gene6064;gene793;gene1109;gene12029;gene1239;gene13591;gene14247;gene14377;gene14378;gene15959;gene16714;gene19988;gene22953;gene266	K00544+K00544+K00016+K00544+K00544+K00789+K01251+K00016+K00827+K08967+K17398+K00544+K00544+K00025+K17989+K01011+K01251+K03334
Ether lipid metabolism	17	61	0.02806649	1.24E-01	ko00565	XLOC_019383;XLOC_019392;XLOC_024611;gene3556;gene4166;gene4696;gene9032;gene9379;gene9990;gene12087;gene14170;gene14169;gene16824;gene17800;gene21714;gene23534;gene2504	K16342+K16342+K16342+K01080+K01080+K16795+K00803+K16860+K16343+K01047+K16342+K16342+K01080+K01080+K01047+K16342+K13510
Jak-STAT signaling pathway	40	172	0.02908268	1.25E-01	ko04630	XLOC_003373;XLOC_020245;XLOC_022319;gene3108;gene3364;gene4502;gene4558;gene5367;gene5545;gene5680;gene6898;gene7631;gene8682;gene8683;gene8862;gene9634;gene9984;gene11177;gene1141;gene1206;gene13531;gene14217;gene15128;gene15142;gene16024;gene16576;gene16617;gene17289;gene17354;gene17669;gene17898;gene18587;gene18990;gene19189;gene19286;gene20211;gene20847;gene22597;gene2231;gene23246	K06854+K05433+K05067+K05134+K02161+K07293+K05061+K02833+K05080+K11222+K10151+K04738+K05076+K05077+K05425+K04696+K05069+K10151+K00922+K04447+K04570+K04694+K02649+K04701+K05423+K05135+K05697+K05074+K04701+K02649+K04696+K05417+K02649+K05077+K04702+K05072+K05058+K05070+K04570+K02161
D-Arginine and D-ornithine metabolism	2	2	0.03030472	1.27E-01	ko00472	gene13685;gene21065	K00273+K00273
alpha-Linolenic acid metabolism	10	31	0.03247684	1.32E-01	ko00592	XLOC_019383;XLOC_019392;XLOC_024611;gene9990;gene12087;gene14170;gene14169;gene17024;gene21714;gene23534	K16342+K16342+K16342+K16343+K01047+K16342+K16342+K00232+K01047+K16342
Proteasome	15	53	0.0331083	1.32E-01	ko03050	XLOC_018652;XLOC_021046;gene5090;gene5091;gene5762;gene7570;gene10456;gene15348;gene15373;gene17419;gene17420;gene20595;gene22266;gene2302;gene2450	K03029+K02738+K02732+K03065+K03028+K10881+K03031+K02737+K02730+K02738+K02741+K02739+K03064+K06699+K03062
Herpes simplex infection	51	232	0.04048836	1.57E-01	ko05168	XLOC_020245;XLOC_024422;gene290;gene3347;gene3563;gene3646;gene4502;gene4997;gene5503;gene6435;gene7171;gene7172;gene7768;gene8147;gene8862;gene863;gene9019;gene9027;gene9063;gene9634;gene9935;gene9947;gene9948;gene11173;gene11360;gene11502;gene1206;gene12921;gene12972;gene13102;gene13238;gene14189;gene14799;gene1486;gene15362;gene15482;gene16225;gene17421;gene17415;gene17723;gene17840;gene17898;gene19059;gene20451;gene20505;gene21456;gene22198;gene2206;gene22954;gene23041;gene23065	K05433+K06752+K05401+K02633+K03130+K05477+K07293+K12647+K11299+K03130+K04379+K04379+K06752+K04519+K05425+K03121+K06751+K04398+K06751+K04696+K05477+K03990+K03990+K12893+K06505+K06505+K04447+K04440+K05653+K15414+K02207+K06081+K14966+K06269+K08860+K12892+K10054+K05654+K06751+K06752+K02373+K04696+K06752+K04519+K09849+K06751+K10159+K03129+K12892+K06752+K05152
Galactose metabolism	12	41	0.04209969	1.59E-01	ko00052	gene3584;gene4311;gene7697;gene9292;gene11838;gene12058;gene12393;gene1294;gene16249;gene16837;gene1939;gene21076	K00963+K01784+K12407+K00850+K01835+K15779+K00965+K00850+K00011+K00844+K12047+K15779
Amino sugar and nucleotide sugar metabolism	17	64	0.0432864	1.60E-01	ko00520	gene2783;gene3584;gene50;gene4311;gene7697;gene11838;gene12058;gene12393;gene14863;gene16162;gene16837;gene19177;gene21076;gene22556;gene23014;gene23013;gene253	K01787+K00963+K00621+K01784+K12407+K01835+K15779+K00965+K00820+K17497+K00844+K01787+K15779+K00698+K01183+K01183+K00966
NOD-like receptor signaling pathway	17	66	0.05625599	1.97E-01	ko04621	gene2961;gene4497;gene8147;gene9027;gene9118;gene9288;gene9317;gene11317;gene12782;gene12895;gene12921;gene17879;gene20451;gene23630;gene263;gene2696;gene275	K12804+K04441+K04519+K04398+K04441+K04079+K12799+K12800+K11859+K08727+K04440+K12801+K04519+K12794+K05482+K09487+K10165
Pyruvate metabolism	14	52	0.05693121	1.97E-01	ko00620	gene5369;gene6556;gene7294;gene8956;gene11918;gene12029;gene12592;gene14754;gene14879;gene15959;gene17304;gene17722;gene18899;gene2085	K00016+K00149+K00626+K00049+K01596+K00016+K00029+K01895+K00128+K00025+K00049+K01596+K00029+K01958
Retinol metabolism	14	52	0.05693121	1.97E-01	ko00830	XLOC_002669;XLOC_009722;XLOC_013621;gene3013;gene4042;gene463;gene5625;gene8920;gene10102;gene10369;gene10841;gene13174;gene13866;gene22539	K00699+K00699+K00699+K00121+K00699+K11155+K07408+K07249+K07424+K00515+K00699+K07437+K00121+K00699
Fatty acid biosynthesis	7	21	0.058531	1.98E-01	ko00061	gene4032;gene4031;gene5918;gene6636;gene7165;gene14450;gene17213	K15013+K15013+K01897+K15013+K01897+K01897+K01897
Focal adhesion	67	326	0.07473132	2.48E-01	ko04510	XLOC_022842;gene2770;gene3254;gene3264;gene3364;gene3540;gene383;gene4122;gene4445;gene4609;gene4700;gene4781;gene5035;gene5367;gene5422;gene6898;gene7242;gene7662;gene7666;gene8473;gene8513;gene8720;gene9483;gene9972;gene9998;gene10158;gene1025;gene1062;gene11177;gene1141;gene12730;gene12793;gene12921;gene12936;gene1298;gene14032;gene14158;gene14218;gene15128;gene1486;gene15422;gene15879;gene15880;gene15881;gene16673;gene16795;gene16921;gene16988;gene17263;gene17408;gene17669;gene17752;gene18186;gene18187;gene18696;gene18990;gene19522;gene21199;gene21309;gene21475;gene22289;gene22465;gene23201;gene23246;gene23307;gene2300;gene2684	K06238+K19662+K05730+K06279+K02161+K05760+K06585+K05089+K05089+K08131+K05732+K16859+K04438+K02833+K12959+K10151+K06244+K05703+K06241+K06272+K05704+K05719+K06525+K07860+K17386+K05448+K00907+K06493+K10151+K00922+K05704+K06237+K04440+K05450+K06238+K05699+K05636+K19662+K02649+K06269+K05730+K05099+K06278+K12958+K06485+K06480+K05448+K06483+K06484+K06237+K02649+K05636+K06238+K06238+K16857+K02649+K04437+K05635+K06238+K06274+K06238+K06238+K05692+K02161+K04410+K04659+K06249
Histidine metabolism	9	31	0.07644888	2.48E-01	ko00340	gene6556;gene8114;gene10837;gene10838;gene11985;gene13987;gene14879;gene19495;gene2709	K00149+K01437+K00546+K00546+K11182+K00129+K00128+K13990+K01745
Aminoacyl-tRNA biosynthesis	12	45	0.07925305	2.52E-01	ko00970	gene471;gene4921;gene667;gene7014;gene9913;gene10378;gene11640;gene12826;gene15551;gene2018;gene23655;gene2469	K14163+K01874+K01887+K01873+K01874+K01881+K01875+K01868+K01870+K01880+K01887+K01867
Protein export	7	23	0.09037268	2.82E-01	ko03060	gene7331;gene7741;gene986;gene10690;gene14722;gene1522;gene19132	K07342+K09481+K09490+K12275+K10956+K12272+K03105
Cell adhesion molecules (CAMs)	50	241	0.09819442	3.00E-01	ko04514	XLOC_013654;XLOC_024422;gene3089;gene383;gene4210;gene4211;gene4606;gene4806;gene4966;gene4989;gene5307;gene5837;gene5970;gene6367;gene6610;gene6613;gene6624;gene7768;gene8238;gene85;gene8720;gene9019;gene9063;gene12629;gene13247;gene13803;gene14189;gene14512;gene14522;gene15629;gene16213;gene16309;gene16454;gene16455;gene16619;gene16673;gene1666;gene16988;gene17415;gene17723;gene18265;gene18626;gene18975;gene19059;gene19241;gene21015;gene21456;gene21987;gene2207;gene23041	K06456+K06752+K03161+K06585+K06770+K06770+K06797+K06592+K06087+K06087+K05718+K06088+K06781+K06471+K06478+K06478+K06088+K06752+K06781+K07377+K05719+K06751+K06751+K06710+K06458+K06471+K06081+K06771+K06771+K06449+K03160+K10785+K06771+K06771+K03160+K06485+K06550+K06483+K06751+K06752+K06087+K06544+K06492+K06752+K10785+K05412+K06751+K06464+K06797+K06752
ECM-receptor interaction	27	122	0.1050454	3.13E-01	ko04512	XLOC_022842;gene383;gene4501;gene4609;gene7242;gene7666;gene8720;gene9483;gene1062;gene12793;gene1298;gene14158;gene16673;gene16795;gene16988;gene17263;gene17408;gene17752;gene18186;gene18187;gene18696;gene21199;gene21309;gene22289;gene22465;gene2300;gene2684	K06238+K06585+K06254+K08131+K06244+K06241+K05719+K06525+K06493+K06237+K06238+K05636+K06485+K06480+K06483+K06484+K06237+K05636+K06238+K06238+K16857+K05635+K06238+K06238+K06238+K04659+K06249
Degradation of aromatic compounds	3	7	0.1064681	3.13E-01	ko01220	gene3013;gene13866;gene18014	K00121+K00121+K01053
Cyanoamino acid metabolism	4	11	0.1086051	3.14E-01	ko00460	gene4930;gene10929;gene15344;gene15345	K00600+K00600+K18592+K18592
Nicotinate and nicotinamide metabolism	11	43	0.1149539	3.23E-01	ko00760	gene5706;gene6929;gene10691;gene12106;gene14408;gene14750;gene15577;gene16398;gene17811;gene20305;gene20909	K10524+K01081+K00858+K00763+K01081+K00323+K10524+K03783+K01242+K03783+K03783
Inositol phosphate metabolism	25	113	0.1157326	3.23E-01	ko00562	gene3193;gene4552;gene4777;gene5064;gene5297;gene6229;gene6487;gene7625;gene8165;gene10344;gene1086;gene11070;gene1141;gene11968;gene12105;gene12227;gene13210;gene13550;gene14885;gene14902;gene1527;gene18936;gene19094;gene19860;gene21831	K00469+K01099+K00140+K15909+K00920+K00140+K00888+K00889+K15909+K03084+K05857+K01858+K00922+K01771+K01116+K13711+K05858+K00889+K00999+K10572+K00911+K01803+K05857+K05857+K00915
mTOR signaling pathway	21	93	0.1197779	3.28E-01	ko04150	gene2770;gene5472;gene5631;gene8588;gene9502;gene10158;gene1141;gene134;gene14218;gene14291;gene1413;gene1456;gene14881;gene15128;gene16004;gene16921;gene17502;gene17669;gene18990;gene197;gene2482	K19662+K08272+K08269+K16172+K07198+K05448+K00922+K08270+K19662+K04688+K03259+K08270+K08269+K02649+K04526+K05448+K08269+K02649+K02649+K03258+K04373
Salmonella infection	23	104	0.1277072	3.44E-01	ko05132	gene4497;gene6056;gene7171;gene7172;gene7454;gene8147;gene9118;gene9260;gene9317;gene10626;gene10648;gene12921;gene15532;gene16666;gene17606;gene19522;gene20451;gene21401;gene21752;gene21896;gene23036;gene23201;gene263	K04441+K05757+K04379+K04379+K05505+K04519+K04441+K05747+K12799+K07863+K10168+K04440+K06071+K12964+K12964+K04437+K04519+K05759+K05505+K05408+K10168+K05692+K05482
ABC transporters	14	59	0.1342211	3.56E-01	ko02010	XLOC_024492;gene710;gene10221;gene10895;gene12772;gene12773;gene12972;gene15687;gene16356;gene17421;gene1742;gene1743;gene18817;gene21290	K05681+K05641+K05643+K05664+K05684+K05683+K05653+K05676+K05681+K05654+K05641+K05641+K05673+K05673
AGE-RAGE signaling pathway in diabetic complications	35	168	0.1405828	3.56E-01	ko04933	gene2770;gene3364;gene4497;gene5367;gene6203;gene8147;gene9118;gene10158;gene1086;gene11395;gene1141;gene11665;gene12105;gene1206;gene12793;gene12921;gene13210;gene14218;gene15128;gene15905;gene16921;gene17408;gene17492;gene17669;gene18259;gene18990;gene19094;gene19286;gene19860;gene20451;gene2041;gene21048;gene21876;gene22657;gene23246	K19662+K02161+K04441+K02833+K13377+K04519+K04441+K05448+K05857+K01398+K00922+K03907+K01116+K04447+K06237+K04440+K05858+K19662+K02649+K04674+K05448+K06237+K06068+K02649+K13375+K02649+K05857+K04702+K05857+K04519+K04166+K08008+K04388+K03982+K02161
Sulfur relay system	4	12	0.1414295	3.56E-01	ko04122	gene17343;gene19988;gene20203;gene20220	K04487+K01011+K03635+K14169
Thiamine metabolism	2	4	0.1424158	3.56E-01	ko00730	gene11914;gene17343	K05307+K04487
Phosphatidylinositol signaling system	30	142	0.143442	3.56E-01	ko04070	gene2770;gene4552;gene4867;gene5064;gene5297;gene6487;gene7625;gene8165;gene10344;gene1086;gene1141;gene12105;gene12227;gene13210;gene13550;gene13658;gene14218;gene14721;gene14885;gene14902;gene15128;gene1527;gene17559;gene17669;gene18990;gene19094;gene19860;gene20081;gene21385;gene21831	K19662+K01099+K00901+K15909+K00920+K00888+K00889+K15909+K03084+K05857+K00922+K01116+K13711+K05858+K00889+K02183+K19662+K07756+K00999+K10572+K02649+K00911+K04960+K02649+K02649+K05857+K05857+K13084+K00901+K00915
Glutathione metabolism	14	60	0.1485793	3.58E-01	ko00480	gene2943;gene4330;gene4442;gene5340;gene5613;gene7722;gene1120;gene12717;gene14709;gene15344;gene15345;gene1838;gene2259;gene23446	K00031+K00799+K00033+K00799+K11140+K00432+K00799+K00432+K00432+K18592+K18592+K00799+K00799+K00799
Tryptophan metabolism	13	55	0.1485994	3.58E-01	ko00380	gene4057;gene5625;gene6556;gene7128;gene7294;gene10415;gene11985;gene1439;gene14879;gene15834;gene18122;gene20361;gene266	K07514+K07408+K00149+K03781+K00626+K00452+K11182+K00164+K00128+K00164+K00164+K00164+K03334
Notch signaling pathway	17	76	0.1598398	3.79E-01	ko04330	gene3291;gene3776;gene5097;gene5656;gene6179;gene7829;gene8183;gene914;gene10481;gene1037;gene12950;gene15051;gene15116;gene15429;gene20519;gene22498;gene22743	K06052+K05948+K06051+K06067+K06051+K06062+K06054+K05948+K06061+K06062+K04496+K06058+K06053+K06058+K06053+K06055+K06051
Citrate cycle (TCA cycle)	10	41	0.1636372	3.83E-01	ko00020	gene2943;gene4488;gene11918;gene1439;gene15834;gene15959;gene17722;gene18122;gene20361;gene2085	K00031+K00235+K01596+K00164+K00164+K00025+K01596+K00164+K00164+K01958
FoxO signaling pathway	43	214	0.1684088	3.88E-01	ko04068	gene279;gene3363;gene4037;gene4497;gene4980;gene5153;gene5367;gene5779;gene5956;gene6203;gene6550;gene6898;gene7128;gene8588;gene9118;gene9502;gene10195;gene10346;gene11177;gene1141;gene11696;gene11918;gene12794;gene12921;gene13968;gene14141;gene15128;gene15584;gene15905;gene16004;gene17669;gene17722;gene18259;gene18990;gene19620;gene20017;gene20211;gene21564;gene21876;gene22154;gene22581;gene22668;gene22724	K16332+K07200+K10146+K04441+K04721+K04527+K02833+K15618+K04402+K13377+K04402+K10151+K03781+K16172+K04441+K07198+K13302+K15618+K10151+K00922+K17845+K01596+K07187+K04440+K10146+K07187+K02649+K17845+K04674+K04526+K02649+K01596+K13375+K02649+K05868+K13303+K05072+K05868+K04388+K07200+K07187+K16332+K04402
Propanoate metabolism	9	37	0.1826805	4.05E-01	ko00640	gene4057;gene4254;gene4777;gene5369;gene6229;gene7294;gene12029;gene14754;gene22572	K07514+K05606+K00140+K00016+K00140+K00626+K00016+K01895+K01908
Steroid hormone biosynthesis	11	47	0.1831703	4.05E-01	ko00140	XLOC_002669;XLOC_009722;XLOC_013621;gene4042;gene5625;gene7487;gene7499;gene10102;gene10841;gene21786;gene22539	K00699+K00699+K00699+K00699+K07408+K00513+K12343+K07424+K00699+K00489+K00699
Drug metabolism - other enzymes	11	47	0.1831703	4.05E-01	ko00983	XLOC_002669;XLOC_009722;XLOC_013621;gene3359;gene4042;gene5011;gene10841;gene15811;gene22539;gene217;gene2417	K00699+K00699+K00699+K00760+K00699+K00757+K00699+K00569+K00699+K01489+K00757
Cytosolic DNA-sensing pathway	12	53	0.2008189	4.37E-01	ko04623	gene8147;gene8961;gene9317;gene15182;gene16164;gene16666;gene17606;gene18611;gene20451;gene21828;gene23273;gene263	K04519+K12671+K12799+K17834+K03022+K12964+K12964+K03023+K04519+K03026+K12671+K05482
"Valine, leucine and isoleucine biosynthesis"	2	5	0.2107483	4.53E-01	ko00290	gene10434;gene16714	K01754+K17989
Lysine degradation	16	75	0.2232101	4.73E-01	ko00310	gene3634;gene4057;gene4956;gene5517;gene6556;gene7294;gene7609;gene1439;gene14879;gene14952;gene15834;gene15872;gene17082;gene18122;gene20361;gene21124	K11703+K07514+K00474+K00471+K00149+K00626+K11420+K00164+K00128+K00306+K00164+K09188+K00473+K00164+K00164+K14157
GnRH signaling pathway	30	150	0.2278438	4.77E-01	ko04912	XLOC_019383;XLOC_019392;XLOC_024611;gene2770;gene4497;gene5205;gene5367;gene7626;gene8513;gene8963;gene9118;gene9575;gene9919;gene11395;gene12730;gene12921;gene13210;gene13424;gene13618;gene13658;gene14170;gene14169;gene14218;gene14461;gene16951;gene17492;gene17559;gene19957;gene23534;gene272	K16342+K16342+K16342+K19662+K04441+K04634+K02833+K04374+K05704+K04515+K04441+K04515+K08049+K01398+K05704+K04440+K05858+K05871+K08041+K02183+K16342+K16342+K19662+K04421+K07763+K06068+K04960+K04515+K16342+K08047
Butirosin and neomycin biosynthesis	2	6	0.2813035	5.81E-01	ko00524	gene7697;gene16837	K12407+K00844
"Valine, leucine and isoleucine degradation"	12	58	0.3033889	6.16E-01	ko00280	gene4057;gene4254;gene4777;gene6229;gene6556;gene7294;gene10202;gene114;gene12148;gene14879;gene20101;gene266	K07514+K05606+K00140+K00140+K00149+K00626+K07509+K09478+K00020+K00128+K01969+K03334
beta-Alanine metabolism	8	37	0.3100419	6.16E-01	ko00410	gene4057;gene4777;gene6229;gene6556;gene7817;gene11600;gene13987;gene14879	K07514+K00140+K00140+K00149+K18966+K00276+K00129+K00128
Biosynthesis of unsaturated fatty acids	8	37	0.3100419	6.16E-01	ko01040	gene7069;gene10900;gene132;gene1453;gene17024;gene17641;gene21142;gene2262	K10703+K17360+K00507+K00507+K00232+K01068+K10203+K10244
Vitamin B6 metabolism	2	7	0.3512377	6.89E-01	ko00750	gene7729;gene9707	K00831+K00275
Arginine biosynthesis	6	28	0.3594451	6.97E-01	ko00220	gene5678;gene979;gene14074;gene15089;gene20804;gene23687	K01425+K01940+K01948+K00611+K11067+K01476
TGF-beta signaling pathway	24	127	0.3636465	6.97E-01	ko04350	gene3001;gene4911;gene4926;gene5200;gene5257;gene5731;gene6203;gene6919;gene7154;gene937;gene10722;gene12561;gene14291;gene14737;gene15463;gene15905;gene1649;gene18259;gene18696;gene1946;gene20646;gene21876;gene22155;gene2214	K04676+K04684+K04667+K13578+K04666+K04662+K13377+K17693+K04662+K13578+K04670+K16791+K04688+K04677+K04667+K04674+K04675+K13375+K16857+K17695+K04662+K04388+K13567+K04680
Vascular smooth muscle contraction	36	195	0.3770501	7.14E-01	ko04270	XLOC_006562;XLOC_019383;XLOC_019392;XLOC_024611;gene2770;gene393;gene5205;gene6401;gene7433;gene8101;gene8120;gene9919;gene9990;gene1025;gene10869;gene11612;gene12087;gene13182;gene13210;gene13513;gene13618;gene13658;gene14170;gene14169;gene14218;gene153;gene1486;gene17148;gene17492;gene17559;gene1737;gene20379;gene2041;gene21714;gene23534;gene272	K08447+K16342+K16342+K16342+K19662+K12333+K04634+K18051+K04136+K04639+K04267+K08049+K16343+K00907+K04266+K04639+K01047+K09821+K05858+K08449+K08041+K02183+K16342+K16342+K19662+K04936+K06269+K18052+K06068+K04960+K12327+K12313+K04166+K01047+K16342+K08047
Regulation of autophagy	7	35	0.4099674	7.67E-01	ko04140	gene5631;gene9502;gene14881;gene16004;gene16318;gene16317;gene17502	K08269+K07198+K08269+K04526+K08342+K08342+K08269
Regulation of actin cytoskeleton	57	317	0.4164528	7.70E-01	ko04810	XLOC_011457;gene2892;gene3254;gene354;gene3540;gene383;gene4122;gene4445;gene4700;gene4902;gene5035;gene5297;gene5307;gene5367;gene5818;gene6056;gene7625;gene8101;gene8287;gene8513;gene8540;gene8720;gene9260;gene9305;gene9483;gene9965;gene9972;gene9998;gene1004;gene1025;gene1062;gene1141;gene11612;gene11677;gene11777;gene12730;gene12936;gene12996;gene13550;gene13704;gene14032;gene15128;gene15187;gene1486;gene15422;gene16004;gene16673;gene16795;gene16988;gene17263;gene17669;gene18990;gene21401;gene21987;gene23201;gene23307;gene23334	K06462+K18496+K05730+K05765+K05760+K06585+K05089+K05089+K05732+K05750+K04438+K00920+K05718+K02833+K05768+K05757+K00889+K04639+K05768+K05704+K05749+K05719+K05747+K05742+K06525+K05766+K07860+K17386+K05093+K00907+K06493+K00922+K04639+K16848+K05768+K05704+K05450+K05762+K00889+K13710+K05699+K02649+K18497+K06269+K05730+K04526+K06485+K06480+K06483+K06484+K02649+K02649+K05759+K06464+K05692+K04410+K06462
Lipoic acid metabolism	1	3	0.4367856	7.89E-01	ko00785	gene19515	K10105
Biotin metabolism	1	3	0.4367856	7.89E-01	ko00780	gene23470	K01435
Sulfur metabolism	3	14	0.4509646	8.06E-01	ko00920	gene14516;gene1487;gene19988	K17725+K01082+K01011
Nitrogen metabolism	4	20	0.4696409	8.24E-01	ko00910	gene1130;gene13090;gene14074;gene22495	K01672+K18246+K01948+K18245
Tyrosine metabolism	8	43	0.4805374	8.24E-01	ko00350	gene3013;gene3859;gene6228;gene11600;gene13866;gene13987;gene21735;gene266	K00121+K01557+K01800+K00276+K00121+K00129+K01555+K03334
Lysosome	29	163	0.4817914	8.24E-01	ko04142	gene2947;gene4076;gene509;gene5076;gene5250;gene6729;gene6941;gene6942;gene7308;gene794;gene8181;gene8581;gene8582;gene9784;gene11007;gene11906;gene13855;gene14039;gene14296;gene15118;gene15180;gene16744;gene18961;gene20020;gene20375;gene21056;gene21500;gene23069;gene2556	K01366+K12393+K06528+K01363+K12382+K14379+K12382+K12382+K06546+K12382+K06562+K01368+K01371+K12388+K04992+K12307+K01158+K01369+K04645+K10532+K12301+K01365+K01074+K12404+K01052+K08568+K12383+K01373+K01134
Synthesis and degradation of ketone bodies	2	9	0.4822415	8.24E-01	ko00072	gene7294;gene2038	K00626+K00019
p53 signaling pathway	17	95	0.4931609	8.34E-01	ko04115	gene4037;gene5956;gene6550;gene6898;gene7306;gene9027;gene9644;gene9903;gene10096;gene11177;gene13968;gene18696;gene19620;gene21564;gene22657;gene22724;gene2680	K10146+K04402+K04402+K10151+K10141+K04398+K02084+K10142+K10141+K10151+K10146+K16857+K05868+K05868+K03982+K04402+K06509
Fatty acid elongation	7	39	0.5307749	8.76E-01	ko00062	gene7069;gene10202;gene10900;gene17641;gene18961;gene21142;gene2262	K10703+K07509+K17360+K01068+K01074+K10203+K10244
ErbB signaling pathway	23	132	0.5353298	8.76E-01	ko04012	gene2770;gene3264;gene5035;gene5367;gene8513;gene8963;gene956;gene9575;gene10950;gene1141;gene11760;gene12105;gene12730;gene12921;gene13626;gene14218;gene14291;gene15128;gene16697;gene17669;gene18990;gene19957;gene23307	K19662+K06279+K04438+K02833+K05704+K04515+K06619+K04515+K09783+K00922+K04707+K01116+K05704+K04440+K08887+K19662+K04688+K02649+K09593+K02649+K02649+K04515+K04410
Glycosphingolipid biosynthesis - lacto and neolacto series	8	45	0.5358184	8.76E-01	ko00601	XLOC_005366;gene5449;gene5828;gene16379;gene19268;gene19805;gene20194;gene2567	K07970+K03766+K00781+K07820+K07970+K07820+K07635+K03494
Selenocompound metabolism	3	16	0.5455486	8.76E-01	ko00450	gene4921;gene8400;gene9913	K01874+K00384+K01874
Pantothenate and CoA biosynthesis	3	16	0.5455486	8.76E-01	ko00770	gene3050;gene7817;gene10112	K09680+K18966+K09680
"Alanine, aspartate and glutamate metabolism"	9	52	0.5655292	8.99E-01	ko00250	gene5678;gene8114;gene9373;gene979;gene1239;gene14074;gene14863;gene20009;gene266	K01425+K01437+K01939+K01940+K00827+K01948+K00820+K01953+K03334
Apoptosis	20	118	0.5918736	9.25E-01	ko04210	gene3315;gene3364;gene4980;gene7631;gene8147;gene9027;gene9644;gene10242;gene1141;gene1289;gene13531;gene15128;gene17669;gene17840;gene18990;gene20451;gene20619;gene2231;gene23236;gene23246	K04723+K02161+K04721+K04738+K04519+K04398+K02084+K04739+K00922+K04724+K04570+K02649+K02649+K02373+K02649+K04519+K04722+K04570+K04722+K02161
Hedgehog signaling pathway	11	65	0.5931675	9.25E-01	ko04340	gene2812;gene3003;gene5731;gene6626;gene7154;gene8904;gene10995;gene1646;gene20646;gene2281;gene2602	K01064+K06231+K04662+K08958+K04662+K06229+K06232+K11990+K04662+K06234+K06226
Riboflavin metabolism	1	5	0.6159491	9.51E-01	ko00740	gene12191	K05901
Glycosaminoglycan biosynthesis - heparan sulfate / heparin	6	37	0.6437913	9.82E-01	ko00534	gene3752;gene6532;gene10719;gene15030;gene15812;gene17943	K07808+K02513+K02366+K02579+K02366+K07809
Homologous recombination	5	31	0.6485481	9.82E-01	ko03440	gene7570;gene7785;gene21641;gene22838;gene2377	K10881+K10867+K03505+K04482+K10875
Folate biosynthesis	4	25	0.6558694	9.84E-01	ko00790	gene5707;gene19167;gene20203;gene21927	K01307+K00287+K03635+K00072
D-Glutamine and D-glutamate metabolism	1	6	0.6828782	1.00E+00	ko00471	gene5678	K01425
Dorso-ventral axis formation	5	34	0.7301165	1.00E+00	ko04320	gene6702;gene8849;gene15236;gene1580;gene23252	K02602+K02602+K02156+K03211+K02602
Other types of O-glycan biosynthesis	7	47	0.7339637	1.00E+00	ko00514	gene3634;gene3776;gene5828;gene651;gene6956;gene914;gene20194	K11703+K05948+K00781+K00779+K13676+K05948+K07635
Taurine and hypotaurine metabolism	3	21	0.7348107	1.00E+00	ko00430	gene7817;gene15344;gene15345	K18966+K18592+K18592
Terpenoid backbone biosynthesis	3	21	0.7348107	1.00E+00	ko00900	gene6949;gene7294;gene9364	K06013+K00626+K12505
Glycosphingolipid biosynthesis - ganglio series	3	21	0.7348107	1.00E+00	ko00604	gene12910;gene1387;gene22869	K00780+K03370+K03370
Progesterone-mediated oocyte maturation	19	125	0.7787448	1.00E+00	ko04914	gene4497;gene6702;gene8849;gene9118;gene9288;gene9862;gene9919;gene1141;gene12921;gene13618;gene15128;gene16004;gene17669;gene18990;gene19620;gene21564;gene23252;gene2482;gene272	K04441+K02602+K02602+K04441+K04079+K04630+K08049+K00922+K04440+K08041+K02649+K04526+K02649+K02649+K05868+K05868+K02602+K04373+K08047
Basal transcription factors	6	43	0.7840584	1.00E+00	ko03022	gene3563;gene6074;gene6404;gene6435;gene863;gene2206	K03130+K02202+K10842+K03130+K03121+K03129
Mucin type O-glycan biosynthesis	6	43	0.7840584	1.00E+00	ko00512	gene11076;gene12910;gene14686;gene1655;gene1678;gene19250	K09663+K00780+K00710+K00731+K00710+K00710
Phenylalanine metabolism	3	23	0.7906843	1.00E+00	ko00360	gene11600;gene13987;gene266	K00276+K00129+K03334
N-Glycan biosynthesis	9	63	0.7919666	1.00E+00	ko00510	gene651;gene11429;gene11577;gene12562;gene16638;gene17061;gene18475;gene18489;gene18815	K00779+K01228+K12670+K00729+K07151+K12666+K01001+K03844+K00738
Sphingolipid metabolism	11	76	0.7944463	1.00E+00	ko00600	gene3556;gene4166;gene11140;gene11403;gene13984;gene16824;gene1676;gene17800;gene20086;gene2441;gene2556	K01080+K01080+K12357+K00654+K04710+K01080+K04715+K01080+K00654+K12352+K01134
Glycosphingolipid biosynthesis - globo series	2	16	0.7955374	1.00E+00	ko00603	gene12910;gene13244	K00780+K00722
RIG-I-like receptor signaling pathway	10	71	0.8146766	1.00E+00	ko04622	gene4497;gene4997;gene8862;gene8961;gene9027;gene9118;gene12921;gene17579;gene17840;gene23273	K04441+K12647+K05425+K12671+K04398+K04441+K04440+K08601+K02373+K12671
Butanoate metabolism	3	24	0.8147349	1.00E+00	ko00650	gene4057;gene7294;gene2038	K07514+K00626+K00019
Gap junction	21	141	0.8175594	1.00E+00	ko04540	gene2770;gene4122;gene4445;gene5205;gene5367;gene6597;gene8186;gene8513;gene9862;gene9919;gene9998;gene12097;gene12730;gene12936;gene13210;gene13347;gene13618;gene14218;gene17559;gene17893;gene272	K19662+K05089+K05089+K04634+K02833+K07374+K04157+K05704+K04630+K08049+K17386+K04289+K05704+K05450+K05858+K07375+K08041+K19662+K04960+K07372+K08047
"Phenylalanine, tyrosine and tryptophan biosynthesis"	1	9	0.8214922	1.00E+00	ko00400	gene266	K03334
Purine metabolism	36	236	0.835861	1.00E+00	ko00230	gene3359;gene4136;gene6929;gene7045;gene8448;gene8806;gene9373;gene9530;gene9578;gene9639;gene9669;gene9919;gene10532;gene11836;gene11838;gene12058;gene13618;gene13752;gene14408;gene14809;gene15112;gene15314;gene16164;gene16398;gene18611;gene18873;gene19302;gene20188;gene20305;gene20909;gene21076;gene21641;gene21828;gene2247;gene2370;gene272	K00760+K01587+K01081+K12304+K01509+K00939+K01939+K13485+K13762+K12304+K01490+K08049+K01466+K13293+K01835+K15779+K08041+K00939+K01081+K13987+K13293+K01487+K03022+K03783+K03023+K13761+K01139+K00944+K03783+K03783+K15779+K03505+K03026+K00856+K19572+K08047
Glycosaminoglycan biosynthesis - keratan sulfate	3	25	0.8363983	1.00E+00	ko00533	gene5828;gene12910;gene2049	K00781+K00780+K04745
Primary bile acid biosynthesis	3	27	0.8732298	1.00E+00	ko00120	gene11406;gene14469;gene21786	K07440+K12408+K00489
Pyrimidine metabolism	17	122	0.8755339	1.00E+00	ko00240	gene5011;gene524;gene6929;gene7045;gene8400;gene9639;gene14408;gene16164;gene16398;gene18611;gene20305;gene20909;gene21641;gene21828;gene217;gene2417;gene2734	K00757+K01520+K01081+K12304+K00384+K12304+K01081+K03022+K03783+K03023+K03783+K03783+K03505+K03026+K01489+K00757+K16330
Calcium signaling pathway	46	309	0.9008936	1.00E+00	ko04020	XLOC_021763;gene2770;gene4122;gene4445;gene5106;gene5205;gene7388;gene7433;gene7925;gene8120;gene8186;gene8863;gene8963;gene9575;gene9919;gene1025;gene10865;gene10869;gene1086;gene12105;gene1214;gene13104;gene13210;gene13424;gene13618;gene13658;gene14218;gene1464;gene1527;gene15779;gene15824;gene15857;gene16309;gene17559;gene17811;gene18118;gene1837;gene19094;gene19241;gene19651;gene19860;gene19957;gene1969;gene2041;gene21642;gene272	K05217+K19662+K05089+K05089+K04223+K04634+K05217+K04136+K00871+K04267+K04157+K04142+K04515+K04515+K08049+K00907+K05853+K04266+K05857+K01116+K04264+K05215+K05858+K05871+K08041+K02183+K19662+K09565+K00911+K05853+K04279+K05862+K10785+K04960+K01242+K09565+K05220+K05857+K10785+K04198+K05857+K04515+K00871+K04166+K05853+K08047
Adherens junction	19	139	0.9045804	1.00E+00	ko04520	gene2793;gene4806;gene5153;gene6674;gene7662;gene8513;gene9260;gene9972;gene11677;gene12730;gene14032;gene14189;gene15879;gene15905;gene16617;gene19224;gene21876;gene21882;gene23201	K05706+K06592+K04527+K06086+K05703+K05704+K05747+K07860+K16848+K05704+K05699+K06081+K05099+K04674+K05697+K04490+K04388+K06083+K05692
MAPK signaling pathway	61	403	0.9067855	1.00E+00	ko04010	XLOC_019383;XLOC_019392;XLOC_024611;gene2770;gene2892;gene3309;gene3310;gene3518;gene46;gene4122;gene4445;gene4497;gene4590;gene5035;gene5367;gene5390;gene5944;gene5956;gene6183;gene6203;gene6550;gene6629;gene7171;gene7172;gene7626;gene8147;gene8694;gene9118;gene9972;gene9998;gene1004;gene11175;gene1108;gene11270;gene11902;gene12284;gene12921;gene13098;gene13257;gene14170;gene14169;gene14218;gene14461;gene15187;gene15603;gene15905;gene16378;gene16451;gene17405;gene18250;gene18259;gene19522;gene19947;gene20451;gene2129;gene21876;gene22374;gene22724;gene23307;gene23534;gene2482	K16342+K16342+K16342+K19662+K18496+K04407+K04387+K04372+K17333+K05089+K05089+K04441+K04459+K04438+K02833+K04459+K04459+K04402+K04350+K13377+K04402+K04372+K04379+K04379+K04374+K04519+K12361+K04441+K07860+K17386+K05093+K04453+K03283+K04454+K04408+K04443+K04440+K04455+K03283+K16342+K16342+K19662+K04421+K18497+K04414+K04674+K04407+K03283+K04861+K04350+K13375+K04437+K04459+K04519+K04381+K04388+K03283+K04402+K04410+K16342+K04373
Base excision repair	4	37	0.9068884	1.00E+00	ko03410	gene6775;gene9262;gene21069;gene21641	K10798+K10772+K03648+K03505
Melanogenesis	20	148	0.9190661	1.00E+00	ko04916	gene2770;gene2812;gene5047;gene5205;gene5367;gene7802;gene8792;gene8963;gene9575;gene9862;gene9919;gene1024;gene13210;gene13618;gene13658;gene14218;gene19224;gene19651;gene19957;gene272	K19662+K01064+K02354+K04634+K02833+K02842+K02842+K04515+K04515+K04630+K08049+K02235+K05858+K08041+K02183+K19662+K04490+K04198+K04515+K08047
RNA polymerase	3	31	0.9255567	1.00E+00	ko03020	gene16164;gene18611;gene21828	K03022+K03023+K03026
Mismatch repair	2	24	0.9389058	1.00E+00	ko03430	gene82;gene21641	K08735+K03505
Oocyte meiosis	18	142	0.9517037	1.00E+00	ko04114	gene6702;gene8849;gene8963;gene9287;gene9575;gene9723;gene9919;gene13097;gene13618;gene13658;gene1486;gene16004;gene17559;gene1788;gene19957;gene23252;gene2482;gene272	K02602+K02602+K04515+K11584+K04515+K08557+K08049+K16198+K08041+K02183+K06269+K04526+K04960+K08557+K04515+K02602+K04373+K08047
2-Oxocarboxylic acid metabolism	2	26	0.9554844	1.00E+00	ko01210	gene2943;gene20804	K00031+K11067
Glycosaminoglycan degradation	2	28	0.9677055	1.00E+00	ko00531	gene12355;gene15118	K01197+K10532
Endocytosis	57	403	0.970481	1.00E+00	ko04144	gene4179;gene4252;gene4444;gene4786;gene5367;gene5422;gene5868;gene6056;gene6126;gene6203;gene6248;gene7625;gene8513;gene8863;gene9019;gene9063;gene9260;gene9984;gene1004;gene10454;gene10491;gene11132;gene1108;gene11499;gene11760;gene11843;gene11844;gene12730;gene13257;gene13530;gene13550;gene14296;gene14611;gene14868;gene15879;gene15880;gene15881;gene15905;gene15951;gene16225;gene16451;gene16752;gene17415;gene17725;gene18259;gene18455;gene18538;gene18977;gene19942;gene20183;gene21456;gene21654;gene21876;gene211;gene22374;gene22597;gene2483	K01528+K19476+K05090+K07941+K02833+K12959+K07905+K05757+K12487+K13377+K07941+K00889+K05704+K04142+K06751+K06751+K05747+K05069+K05093+K12469+K18441+K12473+K03283+K05090+K04707+K12477+K12477+K05704+K03283+K18442+K00889+K04645+K10591+K08291+K05099+K06278+K12958+K04674+K12492+K10054+K03283+K19475+K06751+K12194+K13375+K18441+K12186+K05050+K12484+K12489+K06751+K11247+K04388+K12489+K03283+K05070+K12488
Ribosome biogenesis in eukaryotes	9	85	0.9716108	1.00E+00	ko03008	gene4041;gene8707;gene16740;gene18274;gene18876;gene19135;gene20960;gene21172;gene22611	K14570+K14572+K07178+K14574+K11108+K14536+K03264+K14554+K14550
RNA degradation	10	94	0.9759558	1.00E+00	ko03018	gene3814;gene4875;gene9292;gene12043;gene1294;gene16166;gene16462;gene21402;gene22039;gene2496	K14443+K12571+K00850+K14442+K00850+K14443+K14443+K01689+K03681+K03514
DNA replication	3	40	0.9793355	1.00E+00	ko03030	gene2791;gene16103;gene21641	K02212+K02540+K03505
Cell cycle	20	168	0.9816196	1.00E+00	ko04110	gene2791;gene279;gene5656;gene5893;gene5956;gene5960;gene6074;gene6203;gene6550;gene6898;gene956;gene11177;gene13097;gene16103;gene18259;gene19620;gene21564;gene22668;gene22724;gene2484	K02212+K16332+K06067+K09993+K04402+K06639+K02202+K13377+K04402+K10151+K06619+K10151+K16198+K02540+K13375+K05868+K05868+K16332+K04402+K09389
Other glycan degradation	1	22	0.9852502	1.00E+00	ko00511	gene11140	K12357
Fanconi anemia pathway	5	61	0.987789	1.00E+00	ko03460	gene4069;gene8183;gene1699;gene20992;gene22838	K11832+K06054+K10892+K10888+K04482
Oxidative phosphorylation	18	160	0.9889536	1.00E+00	ko00190	XLOC_012996;gene4488;gene4830;gene9229;gene10560;gene10930;gene11491;gene13532;gene1378;gene1460;gene16184;gene18446;gene19959;gene21169;gene21448;gene21656;gene2169;gene22187	K02270+K00235+K03945+K02270+K03948+K03948+K03962+K02263+K02259+K01507+K02130+K02266+K02270+K02152+K03941+K02265+K00418+K02151
Ubiquitin mediated proteolysis	20	175	0.9897403	1.00E+00	ko04120	gene3063;gene3172;gene4002;gene6324;gene7921;gene8044;gene9634;gene11060;gene11137;gene11760;gene13238;gene14217;gene14611;gene16225;gene16373;gene17487;gene17898;gene19630;gene23019;gene2598	K10260+K07868+K10608+K10447+K10577+K09561+K04696+K10456+K10456+K04707+K02207+K04694+K10591+K10054+K10601+K03871+K04696+K10594+K06689+K10576
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	1	24	0.9899542	1.00E+00	ko00563	gene14608	K05286
Adrenergic signaling in cardiomyocytes	31	252	0.9905939	1.00E+00	ko04261	gene2969;gene3364;gene4497;gene5205;gene7202;gene7433;gene7626;gene8863;gene8963;gene9118;gene9287;gene9305;gene9575;gene9730;gene9862;gene9919;gene1141;gene12683;gene13210;gene13618;gene13658;gene15128;gene1486;gene17405;gene17669;gene18990;gene19957;gene2041;gene21184;gene23246;gene272	K10373+K02161+K04441+K04634+K09052+K04136+K04374+K04142+K04515+K04441+K11584+K05742+K04515+K04167+K04630+K08049+K00922+K01539+K05858+K08041+K02183+K02649+K06269+K04861+K02649+K02649+K04515+K04166+K09052+K02161+K08047
Wnt signaling pathway	23	200	0.9926299	1.00E+00	ko04310	gene2770;gene2812;gene46;gene5047;gene6898;gene7802;gene8792;gene8963;gene9575;gene9581;gene9843;gene9972;gene1024;gene11177;gene12921;gene12950;gene13210;gene14218;gene15276;gene19224;gene19270;gene19957;gene21345	K19662+K01064+K17333+K02354+K10151+K02842+K02842+K04515+K04515+K04508+K04495+K07860+K02235+K10151+K04440+K04496+K05858+K19662+K19614+K04490+K17332+K04515+K02166
Nucleotide excision repair	3	49	0.9947231	1.00E+00	ko03420	gene6074;gene6404;gene21641	K02202+K10842+K03505
SNARE interactions in vesicular transport	2	44	0.9977822	1.00E+00	ko04130	gene9833;gene13677	K08514+K08487
Cardiac muscle contraction	11	133	0.9992569	1.00E+00	ko04260	XLOC_012996;gene2969;gene9229;gene9305;gene12683;gene13532;gene17405;gene18446;gene19959;gene21656;gene2169	K02270+K10373+K02270+K05742+K01539+K02263+K04861+K02266+K02270+K02265+K00418
RNA transport	13	177	0.9999748	1.00E+00	ko03013	gene5282;gene6155;gene7188;gene7921;gene8540;gene14350;gene1413;gene1429;gene15181;gene16515;gene20014;gene1997;gene197	K03231+K03257+K03680+K10577+K05749+K03260+K03259+K14289+K03231+K03262+K03238+K03241+K03258
Phototransduction	1	56	0.9999788	1.00E+00	ko04744	gene13658	K02183
Tight junction	24	270	0.9999837	1.00E+00	ko04530	gene2770;gene3659;gene4966;gene4989;gene5367;gene5837;gene6007;gene6401;gene6624;gene7646;gene8513;gene9505;gene9862;gene9874;gene11774;gene11943;gene12730;gene14032;gene14218;gene17148;gene17492;gene18265;gene21380;gene23201	K19662+K06090+K06087+K06087+K02833+K06088+K06786+K18051+K06088+K06094+K05704+K06091+K04630+K06106+K10352+K06102+K05704+K05699+K19662+K18052+K06068+K06087+K06105+K05692
Neuroactive ligand-receptor interaction	53	493	0.9999928	1.00E+00	ko04080	XLOC_003465;XLOC_021763;gene2890;gene3713;gene3785;gene4817;gene5106;gene48;gene5497;gene5545;gene5687;gene7388;gene7433;gene786;gene8120;gene8129;gene8166;gene8186;gene8450;gene8523;gene8863;gene9730;gene9766;gene10303;gene10304;gene10869;gene11758;gene11756;gene11759;gene11757;gene11958;gene12046;gene12097;gene1214;gene12414;gene12857;gene13104;gene15824;gene16465;gene1672;gene17684;gene18154;gene1837;gene19078;gene19273;gene19651;gene19704;gene20486;gene20753;gene2041;gene2143;gene2164;gene2141	K04265+K05217+K05771+K04292+K01312+K05225+K04223+K04296+K04274+K05080+K04261+K05217+K04136+K04174+K04267+K05222+K04271+K04157+K04269+K04270+K04142+K04167+K04273+K04296+K04296+K04266+K01312+K01312+K01312+K01312+K01312+K04270+K04289+K04264+K01312+K04272+K05215+K04279+K01312+K04228+K04174+K04590+K05220+K04295+K04265+K04198+K04270+K04236+K08397+K04166+K01312+K05771+K01312
mRNA surveillance pathway	4	102	0.9999944	1.00E+00	ko03015	gene9287;gene11347;gene14359;gene1486	K11584+K06965+K03267+K06269
Spliceosome	8	146	0.9999964	1.00E+00	ko03040	gene4316;gene11173;gene1108;gene13257;gene15482;gene16451;gene22374;gene22954	K09564+K12893+K03283+K03283+K12892+K03283+K03283+K12892
Ribosome	3	142	1	1.00E+00	ko03010	gene15705;gene17306;gene17516	K02867+K02881+K02916