class	ID	Descrption	Up	Down	Pvalue
Biological Process	GO:0007155	cell adhesion	50	21	2.83E-26
Biological Process	GO:0022610	biological adhesion	50	21	2.83E-26
Biological Process	GO:0044403	symbiosis, encompassing mutualism through parasitism	23	25	6.57E-19
Biological Process	GO:0044419	interspecies interaction between organisms	23	25	6.57E-19
Biological Process	GO:0051704	multi-organism process	23	25	6.57E-19
Biological Process	GO:0030198	extracellular matrix organization	18	12	4.73E-17
Biological Process	GO:0043062	extracellular structure organization	18	12	4.73E-17
Biological Process	GO:0006928	movement of cell or subcellular component	38	20	3.50E-15
Biological Process	GO:0048870	cell motility	38	20	3.50E-15
Biological Process	GO:0051674	localization of cell	38	20	3.50E-15
Biological Process	GO:0040011	locomotion	41	21	1.28E-14
Biological Process	GO:0008283	cell proliferation	40	27	2.08E-14
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	29	17	2.59E-14
Biological Process	GO:0034330	cell junction organization	15	9	7.44E-14
Biological Process	GO:0048856	anatomical structure development	76	47	7.28E-13
Biological Process	GO:0032502	developmental process	77	50	1.81E-12
Biological Process	GO:0006950	response to stress	60	35	2.83E-12
Biological Process	GO:0002376	immune system process	60	19	9.54E-12
Biological Process	GO:0009653	anatomical structure morphogenesis	36	21	1.13E-11
Biological Process	GO:0008219	cell death	37	27	2.26E-11
Biological Process	GO:0016265	death	37	27	2.26E-11
Biological Process	GO:0044699	single-organism process	113	83	3.10E-11
Biological Process	GO:0050896	response to stimulus	83	59	1.08E-10
Biological Process	GO:0051179	localization	68	53	1.35E-10
Biological Process	GO:0048869	cellular developmental process	62	33	2.12E-10
Biological Process	GO:0044763	single-organism cellular process	107	71	2.50E-10
Biological Process	GO:0030154	cell differentiation	62	31	2.77E-10
Biological Process	GO:0044767	single-organism developmental process	64	37	2.89E-10
Biological Process	GO:0071840	cellular component organization or biogenesis	59	57	3.98E-10
Biological Process	GO:0016043	cellular component organization	59	51	4.84E-09
Biological Process	GO:0007154	cell communication	68	53	3.22E-08
Biological Process	GO:0023052	signaling	68	53	3.22E-08
Biological Process	GO:0044700	single organism signaling	68	53	3.22E-08
Biological Process	GO:0007165	signal transduction	64	51	4.52E-08
Biological Process	GO:0050789	regulation of biological process	64	51	4.52E-08
Biological Process	GO:0050794	regulation of cellular process	64	51	4.52E-08
Biological Process	GO:0051716	cellular response to stimulus	64	51	4.52E-08
Biological Process	GO:0065007	biological regulation	71	52	1.74E-07
Biological Process	GO:0007010	cytoskeleton organization	21	17	1.85E-07
Biological Process	GO:0044085	cellular component biogenesis	29	40	6.49E-07
Biological Process	GO:0007275	multicellular organism development	20	12	7.15E-07
Biological Process	GO:0009790	embryo development	20	12	7.15E-07
Biological Process	GO:0044707	single-multicellular organism process	20	12	7.15E-07
Biological Process	GO:0022607	cellular component assembly	29	34	3.26E-06
Biological Process	GO:0040007	growth	16	12	2.76E-05
Biological Process	GO:0000902	cell morphogenesis	18	8	0.000193002
Biological Process	GO:0032989	cellular component morphogenesis	18	8	0.000193002
Biological Process	GO:0032501	multicellular organismal process	33	18	0.000270831
Biological Process	GO:0006810	transport	46	43	0.000327997
Biological Process	GO:0051234	establishment of localization	46	43	0.000327997
Biological Process	GO:0006605	protein targeting	4	13	0.001147357
Biological Process	GO:0006886	intracellular protein transport	4	13	0.001147357
Biological Process	GO:0008104	protein localization	4	13	0.001147357
Biological Process	GO:0015031	protein transport	4	13	0.001147357
Biological Process	GO:0033036	macromolecule localization	4	13	0.001147357
Biological Process	GO:0034613	cellular protein localization	4	13	0.001147357
Biological Process	GO:0045184	establishment of protein localization	4	13	0.001147357
Biological Process	GO:0070727	cellular macromolecule localization	4	13	0.001147357
Biological Process	GO:0071702	organic substance transport	4	13	0.001147357
Biological Process	GO:0016192	vesicle-mediated transport	24	16	0.001756258
Biological Process	GO:0019439	aromatic compound catabolic process	2	13	0.002244085
Biological Process	GO:0034655	nucleobase-containing compound catabolic process	2	13	0.002244085
Biological Process	GO:0044248	cellular catabolic process	2	13	0.002244085
Biological Process	GO:0044270	cellular nitrogen compound catabolic process	2	13	0.002244085
Biological Process	GO:0046700	heterocycle catabolic process	2	13	0.002244085
Biological Process	GO:1901361	organic cyclic compound catabolic process	2	13	0.002244085
Biological Process	GO:1901575	organic substance catabolic process	2	13	0.002244085
Biological Process	GO:0042254	ribosome biogenesis	0	11	0.003602207
Biological Process	GO:0007568	aging	5	5	0.003994116
Biological Process	GO:0046907	intracellular transport	7	17	0.005149264
Biological Process	GO:0051641	cellular localization	7	17	0.005149264
Biological Process	GO:0051649	establishment of localization in cell	7	17	0.005149264
Biological Process	GO:0051604	protein maturation	6	5	0.007531687
Biological Process	GO:0022613	ribonucleoprotein complex biogenesis	0	13	0.008445623
Biological Process	GO:1902582	single-organism intracellular transport	4	14	0.012272067
Biological Process	GO:0019538	protein metabolic process	34	44	0.014040412
Biological Process	GO:0009987	cellular process	112	91	0.014063033
Biological Process	GO:0003013	circulatory system process	9	4	0.014571555
Biological Process	GO:0006461	protein complex assembly	11	17	0.015527718
Biological Process	GO:0070271	protein complex biogenesis	11	17	0.015527718
Biological Process	GO:0071822	protein complex subunit organization	11	17	0.015527718
Biological Process	GO:0006996	organelle organization	26	22	0.01559533
Biological Process	GO:0010467	gene expression	10	19	0.018909643
Biological Process	GO:0000003	reproduction	16	11	0.020394499
Biological Process	GO:0009056	catabolic process	16	27	0.022516319
Biological Process	GO:0006412	translation	4	12	0.023304835
Biological Process	GO:0006518	peptide metabolic process	4	12	0.023304835
Biological Process	GO:0009059	macromolecule biosynthetic process	4	12	0.023304835
Biological Process	GO:0034645	cellular macromolecule biosynthetic process	4	12	0.023304835
Biological Process	GO:0043043	peptide biosynthetic process	4	12	0.023304835
Biological Process	GO:0043603	cellular amide metabolic process	4	12	0.023304835
Biological Process	GO:0043604	amide biosynthetic process	4	12	0.023304835
Biological Process	GO:0044249	cellular biosynthetic process	4	12	0.023304835
Biological Process	GO:0044271	cellular nitrogen compound biosynthetic process	4	12	0.023304835
Biological Process	GO:1901566	organonitrogen compound biosynthetic process	4	12	0.023304835
Biological Process	GO:1901576	organic substance biosynthetic process	4	12	0.023304835
Biological Process	GO:0043933	macromolecular complex subunit organization	11	21	0.03682813
Biological Process	GO:0065003	macromolecular complex assembly	11	21	0.03682813
Biological Process	GO:0022618	ribonucleoprotein complex assembly	0	6	0.062224295
Biological Process	GO:0034622	cellular macromolecular complex assembly	0	6	0.062224295
Biological Process	GO:0071826	ribonucleoprotein complex subunit organization	0	6	0.062224295
Biological Process	GO:0044267	cellular protein metabolic process	29	41	0.064239424
Biological Process	GO:1901564	organonitrogen compound metabolic process	7	12	0.071922566
Biological Process	GO:0007267	cell-cell signaling	13	14	0.072405264
Biological Process	GO:0006913	nucleocytoplasmic transport	6	4	0.07878149
Biological Process	GO:0016482	cytoplasmic transport	6	4	0.07878149
Biological Process	GO:0051169	nuclear transport	6	4	0.07878149
Biological Process	GO:0007009	plasma membrane organization	5	1	0.113377333
Biological Process	GO:0010256	endomembrane system organization	5	1	0.113377333
Biological Process	GO:0044802	single-organism membrane organization	5	1	0.113377333
Biological Process	GO:0044238	primary metabolic process	49	54	0.120488257
Biological Process	GO:0071704	organic substance metabolic process	49	54	0.120488257
Biological Process	GO:0043170	macromolecule metabolic process	36	47	0.136164703
Biological Process	GO:0003008	system process	16	10	0.169079925
Biological Process	GO:0071941	nitrogen cycle metabolic process	1	0	0.175310573
Biological Process	GO:0061024	membrane organization	13	4	0.17680857
Biological Process	GO:0006464	cellular protein modification process	27	31	0.208266968
Biological Process	GO:0036211	protein modification process	27	31	0.208266968
Biological Process	GO:0043412	macromolecule modification	27	31	0.208266968
Biological Process	GO:0021700	developmental maturation	3	2	0.231910792
Biological Process	GO:0044765	single-organism transport	13	18	0.234523921
Biological Process	GO:1902578	single-organism localization	13	18	0.234523921
Biological Process	GO:0042592	homeostatic process	14	10	0.294994271
Biological Process	GO:0065008	regulation of biological quality	14	10	0.294994271
Biological Process	GO:0006457	protein folding	1	3	0.329397383
Biological Process	GO:0044260	cellular macromolecule metabolic process	31	44	0.339451108
Biological Process	GO:0006629	lipid metabolic process	12	8	0.359512963
Biological Process	GO:0043473	pigmentation	1	1	0.361049483
Biological Process	GO:0007049	cell cycle	10	15	0.361141438
Biological Process	GO:0006139	nucleobase-containing compound metabolic process	6	20	0.417828045
Biological Process	GO:0006725	cellular aromatic compound metabolic process	6	20	0.417828045
Biological Process	GO:0046483	heterocycle metabolic process	6	20	0.417828045
Biological Process	GO:1901360	organic cyclic compound metabolic process	6	20	0.417828045
Biological Process	GO:0019748	secondary metabolic process	1	0	0.50716031
Biological Process	GO:0006091	generation of precursor metabolites and energy	4	2	0.561468084
Biological Process	GO:0006914	autophagy	3	3	0.569755601
Biological Process	GO:0006259	DNA metabolic process	4	8	0.610852423
Biological Process	GO:0051186	cofactor metabolic process	4	1	0.642988406
Biological Process	GO:0008152	metabolic process	66	67	0.72630186
Biological Process	GO:0009058	biosynthetic process	37	41	0.743029147
Biological Process	GO:0007005	mitochondrion organization	4	2	0.749673101
Biological Process	GO:0050877	neurological system process	8	6	0.761425601
Biological Process	GO:0044710	single-organism metabolic process	20	13	0.767171052
Biological Process	GO:0055085	transmembrane transport	11	5	0.776978444
Biological Process	GO:0007034	vacuolar transport	0	1	0.784286065
Biological Process	GO:0000278	mitotic cell cycle	4	6	0.804680177
Biological Process	GO:0006082	organic acid metabolic process	3	0	0.858279772
Biological Process	GO:0006520	cellular amino acid metabolic process	3	0	0.858279772
Biological Process	GO:0019752	carboxylic acid metabolic process	3	0	0.858279772
Biological Process	GO:0043436	oxoacid metabolic process	3	0	0.858279772
Biological Process	GO:0044281	small molecule metabolic process	14	9	0.862680746
Biological Process	GO:0030705	cytoskeleton-dependent intracellular transport	0	1	0.864654461
Biological Process	GO:0051301	cell division	2	3	0.875176302
Biological Process	GO:0090304	nucleic acid metabolic process	4	10	0.951564725
Biological Process	GO:0006396	RNA processing	0	3	0.956156626
Biological Process	GO:0006397	mRNA processing	0	3	0.956156626
Biological Process	GO:0016071	mRNA metabolic process	0	3	0.956156626
Biological Process	GO:0006790	sulfur compound metabolic process	2	0	0.956242066
Biological Process	GO:0044237	cellular metabolic process	50	56	0.966504549
Biological Process	GO:0006807	nitrogen compound metabolic process	33	39	0.978098509
Biological Process	GO:0005975	carbohydrate metabolic process	3	1	0.981449782
Biological Process	GO:0034641	cellular nitrogen compound metabolic process	31	39	0.981578866
Biological Process	GO:0007059	chromosome segregation	0	1	0.988921256
Biological Process	GO:0016070	RNA metabolic process	0	3	0.992715079
Biological Process	GO:0051276	chromosome organization	1	6	0.995396484
Biological Process	GO:0008150	biological_process	124	96	1
Cellular Component	GO:0044421	extracellular region part	77	53	1.71E-33
Cellular Component	GO:0005576	extracellular region	88	55	8.48E-33
Cellular Component	GO:0005615	extracellular space	74	51	1.78E-31
Cellular Component	GO:0005578	proteinaceous extracellular matrix	16	11	7.65E-14
Cellular Component	GO:0031012	extracellular matrix	16	11	7.65E-14
Cellular Component	GO:0005886	plasma membrane	73	40	9.76E-12
Cellular Component	GO:0016020	membrane	73	40	9.76E-12
Cellular Component	GO:0071944	cell periphery	73	40	1.00E-11
Cellular Component	GO:0005829	cytosol	44	49	1.69E-06
Cellular Component	GO:0044444	cytoplasmic part	71	69	4.73E-05
Cellular Component	GO:0005737	cytoplasm	87	78	0.000144641
Cellular Component	GO:0043226	organelle	105	82	0.000244105
Cellular Component	GO:0005856	cytoskeleton	23	22	0.000461609
Cellular Component	GO:0031410	cytoplasmic vesicle	28	16	0.000787258
Cellular Component	GO:0031982	vesicle	28	16	0.000787258
Cellular Component	GO:0043228	non-membrane-bounded organelle	30	39	0.000952533
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	30	39	0.000952533
Cellular Component	GO:0005783	endoplasmic reticulum	22	14	0.002219185
Cellular Component	GO:0005840	ribosome	0	9	0.003263427
Cellular Component	GO:0030529	intracellular ribonucleoprotein complex	0	9	0.003263427
Cellular Component	GO:1990904	ribonucleoprotein complex	0	9	0.003263427
Cellular Component	GO:0000323	lytic vacuole	12	5	0.003546576
Cellular Component	GO:0005764	lysosome	12	5	0.003546576
Cellular Component	GO:0032991	macromolecular complex	32	27	0.004894914
Cellular Component	GO:0005773	vacuole	12	6	0.006260269
Cellular Component	GO:0012505	endomembrane system	36	23	0.009335629
Cellular Component	GO:0005794	Golgi apparatus	19	9	0.014991015
Cellular Component	GO:0043234	protein complex	32	21	0.018177874
Cellular Component	GO:0043229	intracellular organelle	85	78	0.062012301
Cellular Component	GO:0044464	cell part	119	90	0.113178992
Cellular Component	GO:0005730	nucleolus	7	8	0.180757621
Cellular Component	GO:0005768	endosome	11	3	0.180786597
Cellular Component	GO:0005623	cell	119	90	0.187215252
Cellular Component	GO:0044424	intracellular part	97	82	0.192704878
Cellular Component	GO:0005622	intracellular	99	83	0.325300105
Cellular Component	GO:0043227	membrane-bounded organelle	77	58	0.414756874
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	77	58	0.414756874
Cellular Component	GO:0005777	peroxisome	0	2	0.481563122
Cellular Component	GO:0042579	microbody	0	2	0.481563122
Cellular Component	GO:0005634	nucleus	49	39	0.500646076
Cellular Component	GO:0044428	nuclear part	28	23	0.576105851
Cellular Component	GO:0005811	lipid particle	0	1	0.591166505
Cellular Component	GO:0005654	nucleoplasm	19	21	0.618875973
Cellular Component	GO:0031974	membrane-enclosed lumen	25	22	0.623423662
Cellular Component	GO:0031981	nuclear lumen	25	22	0.623423662
Cellular Component	GO:0043233	organelle lumen	25	22	0.623423662
Cellular Component	GO:0070013	intracellular organelle lumen	25	22	0.623423662
Cellular Component	GO:0005815	microtubule organizing center	5	2	0.728938138
Cellular Component	GO:0015630	microtubule cytoskeleton	5	2	0.728938138
Cellular Component	GO:0044430	cytoskeletal part	5	2	0.728938138
Cellular Component	GO:0044422	organelle part	29	24	0.758335951
Cellular Component	GO:0044446	intracellular organelle part	29	24	0.758335951
Cellular Component	GO:0005635	nuclear envelope	3	1	0.795924438
Cellular Component	GO:0031967	organelle envelope	3	1	0.795924438
Cellular Component	GO:0031975	envelope	3	1	0.795924438
Cellular Component	GO:0005739	mitochondrion	11	6	0.862223893
Cellular Component	GO:0005929	cilium	3	1	0.904682265
Cellular Component	GO:0042995	cell projection	3	1	0.904682265
Cellular Component	GO:0000228	nuclear chromosome	3	1	0.924564788
Cellular Component	GO:0005694	chromosome	3	5	0.929988387
Cellular Component	GO:0005575	cellular_component	128	97	1
Molecular Function	GO:0005198	structural molecule activity	20	16	9.29E-13
Molecular Function	GO:0008092	cytoskeletal protein binding	8	17	0.000112202
Molecular Function	GO:0003723	RNA binding	16	22	0.000212307
Molecular Function	GO:0003735	structural constituent of ribosome	0	9	0.000247798
Molecular Function	GO:0005515	protein binding	32	34	0.000257867
Molecular Function	GO:0019843	rRNA binding	0	5	0.000967384
Molecular Function	GO:0030234	enzyme regulator activity	14	11	0.001303844
Molecular Function	GO:0098772	molecular function regulator	14	11	0.001303844
Molecular Function	GO:0005488	binding	73	75	0.003258689
Molecular Function	GO:0019899	enzyme binding	24	18	0.003269196
Molecular Function	GO:0008233	peptidase activity	7	11	0.004445916
Molecular Function	GO:0008134	transcription factor binding	4	9	0.0199185
Molecular Function	GO:0000988	transcription factor activity, protein binding	5	7	0.087423448
Molecular Function	GO:0003729	mRNA binding	1	4	0.109276002
Molecular Function	GO:0044822	poly(A) RNA binding	1	4	0.109276002
Molecular Function	GO:0043167	ion binding	47	40	0.113020065
Molecular Function	GO:0051082	unfolded protein binding	0	3	0.151460435
Molecular Function	GO:0008289	lipid binding	7	4	0.224025296
Molecular Function	GO:0004871	signal transducer activity	15	10	0.251951103
Molecular Function	GO:0016301	kinase activity	4	10	0.2546379
Molecular Function	GO:0016853	isomerase activity	1	2	0.310008599
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	5	10	0.333110919
Molecular Function	GO:0008135	translation factor activity, RNA binding	1	1	0.362366424
Molecular Function	GO:0016787	hydrolase activity	11	17	0.510516219
Molecular Function	GO:0003676	nucleic acid binding	21	26	0.621416849
Molecular Function	GO:0097159	organic cyclic compound binding	21	26	0.621416849
Molecular Function	GO:1901363	heterocyclic compound binding	21	26	0.621416849
Molecular Function	GO:0016874	ligase activity	1	1	0.696835758
Molecular Function	GO:0003924	GTPase activity	1	2	0.707906473
Molecular Function	GO:0016491	oxidoreductase activity	4	4	0.722810907
Molecular Function	GO:0032182	ubiquitin-like protein binding	0	1	0.784683041
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	1	0	0.808190901
Molecular Function	GO:0003824	catalytic activity	23	35	0.816332955
Molecular Function	GO:0016779	nucleotidyltransferase activity	1	0	0.826932075
Molecular Function	GO:0016746	transferase activity, transferring acyl groups	0	2	0.838355875
Molecular Function	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0	1	0.847815233
Molecular Function	GO:0004386	helicase activity	1	0	0.859120395
Molecular Function	GO:0022857	transmembrane transporter activity	9	1	0.864577235
Molecular Function	GO:0030674	protein binding, bridging	1	0	0.886811682
Molecular Function	GO:0060090	binding, bridging	1	0	0.886811682
Molecular Function	GO:0016740	transferase activity	6	12	0.902156075
Molecular Function	GO:0016829	lyase activity	0	1	0.905494672
Molecular Function	GO:0005215	transporter activity	9	1	0.916758117
Molecular Function	GO:0016462	pyrophosphatase activity	2	4	0.924645959
Molecular Function	GO:0016817	hydrolase activity, acting on acid anhydrides	2	4	0.924645959
Molecular Function	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2	4	0.924645959
Molecular Function	GO:0017111	nucleoside-triphosphatase activity	2	4	0.924645959
Molecular Function	GO:0042393	histone binding	0	1	0.925074224
Molecular Function	GO:0004518	nuclease activity	0	1	0.938265451
Molecular Function	GO:0001071	nucleic acid binding transcription factor activity	6	4	0.956962523
Molecular Function	GO:0016791	phosphatase activity	1	0	0.971596799
Molecular Function	GO:0042578	phosphoric ester hydrolase activity	1	0	0.971596799
Molecular Function	GO:0016757	transferase activity, transferring glycosyl groups	1	0	0.974395186
Molecular Function	GO:0016887	ATPase activity	0	2	0.976381777
Molecular Function	GO:0016788	hydrolase activity, acting on ester bonds	1	1	0.987104246
Molecular Function	GO:0003677	DNA binding	8	8	0.999568755
Molecular Function	GO:0003674	molecular_function	126	92	1